hCD44v9/MC-38
CBPG0282
询 价
留 言
产品描述
产品数据库
| I. Background | |
| CD44v9是CD44基因的可变剪接变异体，在多种上皮性肿瘤和肿瘤干细胞表面高表达。它顺利获得与xCT（胱氨酸/谷氨酸转运蛋白）相互作用，增强细胞内谷胱甘肽合成，清除活性氧，从而赋予肿瘤细胞抗氧化应激和耐药能力，并促进肿瘤侵袭、转移和复发。其高表达通常提示预后不良，是重要的肿瘤标志物和潜在治疗靶点。 | |
| II. Introduction | |
| Host Cell: | MC-38 |
| Expressed gene: | CD44v9 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Mus musculus, mouse |
| Tissue: | Colon |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| IV. Representative Data | |
|
|
|
